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Hypothyroidism is the disease state in humans andin vertebratescaused by insufficient production of thyroidhormone by the thyroid gland. Cretinism isa form of hypothyroidism found in infants


In adults, hypothyroidism is associated with the following symptoms

Early symptoms

Late symptoms

  • Slow speech and a hoarse, breaking voice – deepening of the voice can also be noticed
  • Dry puffy skin, especially on the face
  • Thinning of the outer third of the eyebrows
  • Abnormal menstrual cycles
  • Low basal body temperature

Less common symptoms

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